Luxembourg's Prince Frederik Passes Away at 22 Following Rare Genetic Disease

Luxembourg mourns the loss of Prince Frederik, who has died at age 22 after enduring a long struggle with PolG mitochondrial disease, a hereditary genetic disorder. Born to Prince Robert and Princess Julie, he was diagnosed with this rare condition at age 14.

On March 7, Prince Robert announced that Frederik passed away in Paris on March 1. In a poignant farewell, Frederik spoke to his parents and siblings, one final time before he died. "Frederik's last question to me was: 'Papa, are you proud of me?'" Robert shared on the PolG Foundation's website, emphasizing the gravity of the moment.

Robert highlighted that while pride was an easy response, Frederik needed assurance of his life's impact. "He could finally move on," Robert said, acknowledging Frederik's profound influence on his family, friends, and the many people supported by the PolG Foundation.

In those final moments, Frederik shared personal messages. He left kindest words with his mother, who remained by his side for 15 years. The late prince's father noted their family humor endured until the end, as Frederik aimed to uplift those around him. "Even in his last moments, he brought us one last laugh," Robert recalled.

Frederik, just weeks shy of his 23rd birthday, faced PolG mitochondrial disease, characterized by mutations that led to organ failures. He poignantly stated in a film released by the PolG Foundation, "As a kid, your dreams are endless. But PolG makes the world smaller."

Despite the challenges, Prince Robert expressed that Frederik did not want the disease to define him. However, it ultimately shaped the mission of the POLG Foundation, where Frederik channeled his creative talents. A family friend recounted Frederik’s words of acceptance, noting, "I’m glad I’m the one with this disease. Even if I die, I know my parents can save other children."

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